Retrospective Cohort Study
Copyright ©The Author(s) 2024.
World J Clin Cases. Feb 26, 2024; 12(6): 1063-1075
Published online Feb 26, 2024. doi: 10.12998/wjcc.v12.i6.1063
Figure 1
Figure 1 Flowchart of the study. AD: Alzheimer’s disease.
Figure 2
Figure 2 Magnetic resonance imaging and corresponding magnetic spectroscopy images of an Alzheimer’s disease patient. The patient was a 55-year-old female with a 4-year course of disease and a Mini Mental State Examination Scale score of 14 points. A: Magnetic resonance imaging images (axial view) of the patient showed mild degeneration and atrophy in the hippocampus, deepening of multiple cerebral sulcus, suggesting mild brain atrophy; B: The corresponding magnetic spectroscopy pictures of the patient showed N-acetylaspartate 37mmol/L, creatine 26 mmol/L, and choline 39 mmol/L, indicating that there was a metabolic disorder of brain neurotransmitters.
Figure 3
Figure 3 Lymphocyte subsets in the blood of Alzheimer’s disease patients were detected by flow cytometry. A: T cell was detected by using Anti-human CD3e-PE (ebioscience); B: B cells were detected by using Anti-Human CD19-PerCP (BioLegend); C: Natural killer cells were detected by using anti-human CD56-APC (ebioscience). NK: Natural killer.
Figure 4
Figure 4 Receptor working curve of the predictive value of N-acetylaspartate/creatine ratio of magnetic spectroscopy for poor prognosis of Alzheimer’s disease. ROC: Receptor working curve.