Li T, Sun XD, Yu Y, Lv GY. Intra-arterial thrombolysis for early hepatic artery thrombosis after liver transplantation. World J Clin Cases 2021; 9(7): 1592-1599 [PMID: 33728302 DOI: 10.12998/wjcc.v9.i7.1592]
Corresponding Author of This Article
Guo-Yue Lv, PhD, Professor, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. lgy08@sina.com
Research Domain of This Article
Transplantation
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Mar 6, 2021; 9(7): 1592-1599 Published online Mar 6, 2021. doi: 10.12998/wjcc.v9.i7.1592
Intra-arterial thrombolysis for early hepatic artery thrombosis after liver transplantation
Ting Li, Xiao-Dong Sun, Ying Yu, Guo-Yue Lv
Ting Li, Xiao-Dong Sun, Ying Yu, Guo-Yue Lv, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Li T collected, analyzed data and wrote the paper; Sun XD performed the study; Yu Y collected the data; Lv GY designed and supervised the study.
Supported byThe Science and Technology Department of Jilin Province, No. 20180622004JC and No. 20190101002JH; and the Finance Department of Jilin Province, No. 2017F004 and No. 2018SCZWSZX-044.
Institutional review board statement: This research was approved by the Ethical Committee of First Hospital of Jilin University.
Conflict-of-interest statement: The authors have no conflict of interest to disclose.
Data sharing statement: Original data are available from the corresponding author at lgy08@sina.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Yue Lv, PhD, Professor, Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun 130021, Jilin Province, China. lgy08@sina.com
Received: October 26, 2020 Peer-review started: October 26, 2020 First decision: December 8, 2020 Revised: December 22, 2020 Accepted: December 28, 2020 Article in press: December 28, 2020 Published online: March 6, 2021
Core Tip
Core Tip: This retrospective study evaluated the feasibility and reasonability of intra-arterial thrombolysis for early hepatic artery thrombosis (E-HAT) after deceased donor liver transplantation. The incidence of E-HAT was 2.7% (4/147). The patients were given temporary thrombolytics followed by continuous alteplase using an infusion pump. Alteplase dose was adjusted according to activated clotting time. The recanalization rate of intra-arterial thrombolysis in our study was 100% and no thrombolysis-related mortality was observed. Intra-arterial thrombolysis can be considered first-line treatment for E-HAT after deceased donor liver transplantation. Early diagnosis of E-HAT is important and follow-up is necessary even if recanalization is successful.
