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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2021; 9(32): 9815-9824
Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9815
Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9815
Association between Helicobacter pylori infection and food-specific immunoglobulin G in Southwest China
Ying Liu, Ping Shuai, Yu-Ping Liu, Dong-Yu Li, Health Management Center, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 611731, Sichuan Province, China
Ying Liu, Ping Shuai, Yu-Ping Liu, Dong-Yu Li, Health Management Center, Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu 610072, Sichuan Province, China
Author contributions: Liu Y and Li DY contributed to the conception and design of the work; Liu Y and Shuai P contributed to the acquisition, analysis and interpretation of data for the study; Liu Y contributed to drafting the work; Li DY and Liu YP revised the manuscript; Li DY was accountable for all aspects of the work.
Supported by Key Research and Development Projects of the Ministry of Science and Technology , China, No. 2017YFC0113901.
Institutional review board statement: The study was reviewed and approved by the Ethical Committee of Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital [Approval No. 408(2020)].
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong-Yu Li, MD, Doctor, Health Management Center, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, No. 32 Section 2, West 1st Ring Road, Qingyang District, Chengdu 611731, Sichuan Province, China. dongyuzhiyin@163.com
Received: June 27, 2021
Peer-review started: June 27, 2021
First decision: July 14, 2021
Revised: July 19, 2021
Accepted: September 1, 2021
Article in press: September 1, 2021
Published online: November 16, 2021
Peer-review started: June 27, 2021
First decision: July 14, 2021
Revised: July 19, 2021
Accepted: September 1, 2021
Article in press: September 1, 2021
Published online: November 16, 2021
Core Tip
Core Tip: This is a retrospective study to evaluate the association of Helicobacter pylori (H. pylori) infection and food-specific immunoglobulin G. We analyzed the data of 21822 subjects who underwent H. pylori infection assessment by the urea breath test and testing for food-specific immunoglobulin G of eggs, milk and wheat. The key finding was that H. pylori infection was associated with lower positivity for food-specific immunoglobulin G. If the negative correlation could be further confirmed and the mechanism could be clarified, it would provide some advisable suggestions for medical decisions regarding asymptomatic H. pylori infection.