Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 5860-5872
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5860
Development and validation of a prognostic nomogram for colorectal cancer after surgery
Bo-Wen Li, Xiao-Yu Ma, Shuang Lai, Xin Sun, Ming-Jun Sun, Bing Chang
Bo-Wen Li, Shuang Lai, Xin Sun, Bing Chang, Department of Gastroenterology, The Frist Hospital of China Medical University, Shenyang 110000, Liaoning Province, China
Xiao-Yu Ma, Ming-Jun Sun, Department of Gastroenterology and Endoscopy, The Frist Hospital of China Medical University, Shenyang 110000, Liaoning Province, China
Author contributions: Li BW performed the research and wrote the paper; Ma XY supervised the report; Lai S and Sun X contributed to the analysis; Sun MJ and Chang B proposed the idea and clinical advice.
Supported by Science and Technology Support Program of Shenyang, No. 20-205-4-094.
Institutional review board statement: The experimental data are from the Surveillance, Epidemiology, and End Results (SEER) database, not clinical cases from any medical institutions. Therefore, our research does not need to be approved by an ethics committee.
Informed consent statement: The experimental data are from the Surveillance, Epidemiology, and End Results (SEER) database, not clinical cases from any medical institutions. Because the data is anonymous and the patients’ personal privacy information is not available, informed consent is not required.
Conflict-of-interest statement: The authors have no conflict of interest to declare.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bing Chang, MD, Assistant Professor, Department of Gastroenterology, The Frist Hospital of China Medical University, No. 155 Nanjing North Street, Shenyang 110000, Liaoning Province, China. cb000216@163.com
Received: February 25, 2021
Peer-review started: February 25, 2021
First decision: May 1, 2021
Revised: May 17, 2021
Accepted: May 25, 2021
Article in press: May 25, 2021
Published online: July 26, 2021
Core Tip

Core Tip: The Surveillance, Epidemiology, and End Results (SEER) program has provided material and data support for evidence-based clinical studies. At present, few studies have concentrated on developing a predictive model for the outcomes of colorectal cancer (CRC) after surgery. We developed a nomogram to predict the probability of overall survival at different times in patients with CRC based on the SEER database. Compared with the N staging from the American Joint Committee on Cancer tumor-node-metastasis classification, the nomogram incorporating the log odds of positive lymph nodes and tumor deposit in this study showed better sensitivity and specificity.