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World J Clin Cases. Jul 26, 2021; 9(21): 5769-5781
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.5769
Prevention of hepatitis B reactivation in patients requiring chemotherapy and immunosuppressive therapy
Chih-An Shih, Wen-Chi Chen
Chih-An Shih, Wen-Chi Chen, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan
Chih-An Shih, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Antai Medical Care Corporation, Antai Tian-Sheng Memorial Hospital, Pingtung County 928, Taiwan
Chih-An Shih, Department of Nursing, Meiho University, Pingtung County 928, Taiwan
Wen-Chi Chen, Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan
Wen-Chi Chen, Institute of Biomedical Sciences, College of Science, National Sun Yat-sen University, Kaohsiung 8424, Taiwan
Author contributions: Shih CA and Chen WC designed the research study, performed the research and wrote the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare having no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Chi Chen, MD, Chief Doctor, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, No. 386 Ta-Chung 1st Road, Kaohsiung 813, Taiwan. wcchen@vghks.gov.tw
Received: January 29, 2021
Peer-review started: January 29, 2021
First decision: March 29, 2021
Revised: April 12, 2021
Accepted: June 2, 2021
Article in press: June 2, 2021
Published online: July 26, 2021
Core Tip

Core Tip: Reactivation of hepatitis B virus (HBV) could be fatal in the patients with hepatitis B infection and chemotherapy or immunosuppressive therapy. We review the risk of HBV reactivation, screening of HBV infection and the strategies of prophylaxis of HBV reactivation in patients requiring chemotherapy and immunosuppressive therapy.