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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2020; 8(7): 1278-1286
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1278
Published online Apr 6, 2020. doi: 10.12998/wjcc.v8.i7.1278
Chidamide based combination regimen for treatment of monomorphic epitheliotropic intestinal T cell lymphoma following radical operation: Two case reports
Ting-Zhi Liu, Yi-Jia Zheng, Jiao-Ting Chen, Ai-Hua Peng, Ren-Wei Huang, Department of Hematology, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Zhan-Wen Zhang, Department of Nuclear Medicine, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Shan-Shan Li, Department of Oncology, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Author contributions: Liu TZ acquired the data and drafted the article; Zheng YJ, who was the resident physician of case two, analyzed the data and drafted the article; Zhang ZW analyzed and interpreted the imaging findings; Li SS helped revise the article; Chen JT, who was the resident physician of case one, analyzed the data; Peng AH and Huang RW, who were the chief physicians of cases one and two, revised the manuscript for important intellectual content. All authors issued final approval for the version to be submitted.
Informed consent statement: We obtained written informed consent from patients before treatment administering. When we did this retrospective analysis, we obtained oral informed consent from their relatives for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ren-Wei Huang, MD, Professor, Chief Doctor, Department of Hematology, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancun Erheng Road, Guangzhou 510655, Guangdong Province, China. huangrw56@163.com
Received: December 24, 2019
Peer-review started: December 24, 2019
First decision: March 5, 2020
Revised: March 18, 2020
Accepted: March 22, 2020
Article in press: March 22, 2020
Published online: April 6, 2020
Peer-review started: December 24, 2019
First decision: March 5, 2020
Revised: March 18, 2020
Accepted: March 22, 2020
Article in press: March 22, 2020
Published online: April 6, 2020
Core Tip
Core tip: Monomorphic epitheliotropic intestinal T cell lymphoma (MEITL) is a rare and aggressive disease with a poor prognosis. No standardized treatment has been established yet. We report two cases of patients with MEITL who were treated by radical resection followed by chidamide combined with chemotherapy and review the literature focusing on histopathological characteristics, etiology, diagnosis, treatment strategies, and outcomes of MEITL. This report will improve our understanding of MEITL.