Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2020; 8(21): 5313-5319
Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5313
Diffusion-weighted imaging might be useful for reactive lymphoid hyperplasia diagnosis of the liver: A case report
Taro Tanaka, Kazuhiro Saito, Daisuke Yunaiyama, Jun Matsubayashi, Yuichi Nagakawa, Maki Tanigawa, Toshitaka Nagao
Taro Tanaka, Kazuhiro Saito, Daisuke Yunaiyama, Department of Radiology, Tokyo Medical University, Tokyo 1600023, Japan
Jun Matsubayashi, Maki Tanigawa, Toshitaka Nagao, Department of Anatomic Pathology, Tokyo Medical University, Tokyo 1600023, Japan
Yuichi Nagakawa, Department of Gastrointestinal and Pediatric Surgery, Tokyo Medical University, Tokyo 1600023, Japan
Author contributions: Tanaka T researched the literature and drafted the manuscript; Saito K reviewed the literature and edited the manuscript; Nagakawa Y edited the paper and suggested clinical information; Yunaiyama D, Matsubayashi J, Tanigawa M and Nagao T edited the pathological portions of the manuscript.
Informed consent statement: Informed consent was obtained in a routine manner.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Taro Tanaka, MD, Assistant Professor, Department of Radiology, Tokyo Medical University, 6-7-1, Nishi-Shinjuku, Shinjuku-ku, Tokyo 1600023, Japan. gossip.auction@hotmail.co.jp
Received: July 8, 2020
Peer-review started: July 8, 2020
First decision: August 8, 2020
Revised: August 22, 2020
Accepted: September 22, 2020
Article in press: September 22, 2020
Published online: November 6, 2020
Core Tip

Core Tip: Reactive lymphoid hyperplasia of the liver is a rare liver lesion. It is known to be difficult to differentiate radiologically from hepatocellular carcinoma, metastatic liver tumor and other pathologies. We encountered a new radiologic characteristic finding on diffusion-weighted imaging. This new finding was linear hyperintensity along the portal tract, consecutive to the liver lesion and corresponded to the lymphoid cell infiltration of the portal tract. Perinodular enhancement in the arterial phase or equilibrium phase on contrast-enhanced computed tomography and magnetic resonance imaging indicated lymphocytic infiltration.