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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2020; 8(18): 4169-4176
Published online Sep 26, 2020. doi: 10.12998/wjcc.v8.i18.4169
Published online Sep 26, 2020. doi: 10.12998/wjcc.v8.i18.4169
Insulinoma presenting with postprandial hypoglycemia and a low body mass index: A case report
Dana Prídavková, Matej Samoš, Margita Belicová, Marián Mokáň, Clinic of Internal Medicine I, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Martin 03601, Slovakia
Roman Kyčina, Clinic of Surgery and Transplant Center, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Martin 03601, Slovakia
Katarína Adamicová, Michal Kalman, Department of Pathological Anatomy, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Martin 03601, Slovakia
Author contributions: Prídavková D participated in the conception and design of the report and wrote the paper; Kyčina R, Adamicová K, Kalman M, Belicová M and Mokáň M made substantial contributions to the acquisition, analysis and interpretation of the patient data; Samoš M and Belicová M were involved in the coordination and design of the report and revision of the manuscript; all authors read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Dana Prídavková, MD, PhD, Doctor, Medical Assistant, Clinic of Internal Medicine I, Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Kollárova 2, Martin 03601, Slovakia. danapridavkova@gmail.com
Received: May 29, 2020
Peer-review started: May 29, 2020
First decision: June 13, 2020
Revised: June 23, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 26, 2020
Peer-review started: May 29, 2020
First decision: June 13, 2020
Revised: June 23, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 26, 2020
Core Tip
Core Tip: Postprandial hypoglycemia and hypoglycemia following physical exercise associated with unconsciousness/amnesia and a low body weight were the clinical features of insulinoma in a 24-year-old man for over 6 years. The consequences of the chronic counterregulatory adrenergic response were also indirectly indicated by the increased metabolic activity of brown adipose tissue and decrease in muscle glycogen content, although the fasting test and other imaging results were initially evaluated as normal. Therefore, if insulinoma is clinically suspected, the fasting test should be repeated. The patient was underweight with a very small amount of visceral fat, which increases the risk of perioperative complications.