Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2020; 8(15): 3299-3304
Published online Aug 6, 2020. doi: 10.12998/wjcc.v8.i15.3299
Hypothyroidism with elevated pancreatic amylase and lipase without clinical symptoms: A case report
Yong-Wei Xu, Ran Li, Shu-Chang Xu
Yong-Wei Xu, Shu-Chang Xu, Department of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China
Ran Li, Department of Endocrinology and Metabolism, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, China
Author contributions: Xu YW drafted the manuscript; Xu YW and Li R analyzed the data; Xu SC revised the article critically; all authors read and approved the final manuscript.
Supported by Shanghai Shenkang Hospital Development Center, No. SHDC12016109.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shu-Chang Xu, PhD, MD, Chief Doctor, Professor, Department of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, No. 389 Xincun Road, Putuo District, Shanghai 200065, China. xschang@163.com
Received: March 21, 2020
Peer-review started: March 21, 2020
First decision: April 24, 2020
Revised: April 30, 2020
Accepted: July 15, 2020
Article in press: July 15, 2020
Published online: August 6, 2020
Core Tip

Core tip: Hypothyroidism is an endocrine disorder that has worldwide prevalence and can affect multiple organ systems. However, even when pancreatic amylase and lipase are elevated, hypothyroidism without acute pancreatitis rarely causes clinical symptoms. Here, we report a case of hypothyroidism leading to elevated trypsin without acute pancreatitis in a patient who had no clinical symptoms. This case report can serve as a reminder to gastroenterologists, emergency physicians, and surgeons who encounter these cases in clinical practice.