Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2020; 8(13): 2769-2777
Published online Jul 6, 2020. doi: 10.12998/wjcc.v8.i13.2769
Published online Jul 6, 2020. doi: 10.12998/wjcc.v8.i13.2769
Correlation between age of onset and gastrointestinal stenosis in hospitalized patients with Crohn's disease
Shan-Bing Yang, Shu-Wen Du, Ji-Heng Wang, Department of Gastroenterology, the Seventh Medical Center, Chinese People’s Liberation Army General Hospital, Beijing 100700, China
Author contributions: Yang SB and Du SW contributed equally to this paper.
Supported by Capital Health Development Research Fund , No. 2018-1-5091 ; National Key R and D Program of China , No. 2017YFC0112304 .
Institutional review board statement: The study was reviewed and approved for publication by our Institutional Reviewer.
Informed consent statement: Due to the nature of the retrospective study, informed consent from all study participants was waived.
Conflict-of-interest statement: All the authors have no conflict of interest related to the manuscript.
Data sharing statement: The original anonymous dataset is available on request from the corresponding author at E-mail: lileiyouan@ccmu.edu.cn.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ji-Heng Wang, PhD, Chief Doctor, the Seventh Medical Center, Chinese People’s Liberation Army General Hospital, No.5, Nanmengcang Hutong, Beijing 100700, China. lileiyouan@ccmu.edu.cn
Received: March 3, 2020
Peer-review started: March 3, 2020
First decision: April 25, 2020
Revised: May 26, 2020
Accepted: June 13, 2020
Article in press: June 13, 2020
Published online: July 6, 2020
Peer-review started: March 3, 2020
First decision: April 25, 2020
Revised: May 26, 2020
Accepted: June 13, 2020
Article in press: June 13, 2020
Published online: July 6, 2020
Core Tip
Core tip: We retrospectively analyzed the clinical information of 122 cases of hospitalized patients with Crohn's disease. Demographics, disease activity, classification, treatment, and complications were compared between patients with and without gastrointestinal stenosis. It was found that age of onset of more than 40 years and duration of disease of more than 5 years were correlated with the occurrence of gastrointestinal stenosis. Endoscopic therapy has gradually become one of the main methods for the treatment of Crohn's disease-related gastrointestinal stenosis due to its safe and effective characteristics.