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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 6, 2019; 7(23): 3934-3944
Published online Dec 6, 2019. doi: 10.12998/wjcc.v7.i23.3934
Published online Dec 6, 2019. doi: 10.12998/wjcc.v7.i23.3934
Value of early diagnosis of sepsis complicated with acute kidney injury by renal contrast-enhanced ultrasound
Xiu-Yan Wang, Yan-Ping Pang, Tian Jiang, Shuo Wang, Department of Ultrasound, Tongji Hospital of Tongji University, Shanghai 200065, China
Jiang-Tao Li, Chen Yu, Department of Nephrology, Tongji Hospital of Tongji University, Shanghai 200065, China
Bao-Min Shi, Department of General Surgery, Tongji Hospital of Tongji University, Shanghai 200065, China
Author contributions: Wang XY and Pang YP contributed equally to this manuscript; Wang XY, Pang YP, Shi BM, and Yu C designed the research; Wang XY, Pang YP, Jiang T, Li JT, and Yu C performed the research; Pang YP, Wang S, and Shi B contributed new analytic tools; Wang XY, Wang S, Li JT, and Yu C analyzed the data; and Wang XY, Pang YP, Jiang T, Wang S, Li JT, Shi BM, and Yu C wrote the paper.
Supported by National Natural Science Foundation of China , No. 81873609 .
Institutional review board statement: The study was approved by the ethics committee of Tongji Hospital of Tongji University.
Informed consent statement: All patients gave informed consent.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE statement, and the manuscript was prepared and revised according to the STROBE statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Bao-Min Shi, PhD, Chief Physician, Professor, Department of General Surgery, Tongji Hospital of Tongji University, No. 389 Xincun Road, Putuo District, Shanghai 200065, China. baominsph@163.com
Telephone: +86-18019178659
Received: September 6, 2019
Peer-review started: September 6, 2019
First decision: October 24, 2019
Revised: October 30, 2019
Accepted: November 20, 2019
Article in press: November 20, 2019
Published online: December 6, 2019
Peer-review started: September 6, 2019
First decision: October 24, 2019
Revised: October 30, 2019
Accepted: November 20, 2019
Article in press: November 20, 2019
Published online: December 6, 2019
Core Tip
Core tip: Early detection of risk factors for septic acute kidney injury (AKI) and early intervention are important for the treatment of patients with sepsis. Currently, serum creatinine (SCr) is used as the criterion for AKI diagnosis. But SCr has obvious hysteresis and poor sensitivity, and it is difficult to predict the occurrence of early septic AKI. In this study, contrast-enhanced ultrasound techniques were utilized to explore the value of early diagnosis of septic AKI, and it revealed that the combination of SCr, peak intensity, and wash in slope (contrast-enhanced ultrasound indicators) can improve the early diagnosis of septic AKI.