Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.2963
Peer-review started: July 14, 2019
First decision: August 2, 2019
Revised: August 9, 2019
Accepted: August 20, 2019
Article in press: August 20, 2019
Published online: October 6, 2019
Core tip: At present, the clinical evaluation of osteoarthritis relies on VAS score, Lysholm score, and WOMAC score and other scales. These scales have a common deficiency, i.e., they are affected by a certain degree of subjective factors. Many clinical workers use Kellgren-Lawrence (K-L) grading to evaluate the therapeutic effect of patients with osteoarthritis, but the K-L grading depends on imaging, the effect of radiation on the human body and the medical expenses are high, and it takes a long time. This study explored the clinical value of miR-145 and inflammatory factors in peripheral blood, and explored the application of serological analysis in the diagnosis and treatment of osteoarthritis, so as to provide a reference for the diagnosis and treatment of osteoarthritis.