Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Dec 16, 2014; 2(12): 859-865
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.859
Published online Dec 16, 2014. doi: 10.12998/wjcc.v2.i12.859
Role of immunotherapy in the treatment of allergic asthma
Ayfer Yukselen, Clinic of Pediatric Allergy and Immunology, Gaziantep Children Hospital, Sehitkamil, 27310 Gaziantep, Turkey
Seval Guneser Kendirli, Division of Pediatric Allergy and Immunology, Cukurova University Faculty of Medicine, Balcali, 01150 Adana, Turkey
Author contributions: Yukselen A wrote the paper; and Kendirli SV reviewed the paper.
Correspondence to: Ayfer Yukselen, MD, Associate Professor of Pediatrics, Clinic of Pediatric Allergy and Immunology, Gaziantep Children Hospital, Sehitkamil, 27560 Gaziantep, Turkey. ayfyukselen@gmail.com
Telephone: +90-342-2200072
Received: July 27, 2014
Revised: August 27, 2014
Accepted: October 14, 2014
Published online: December 16, 2014
Revised: August 27, 2014
Accepted: October 14, 2014
Published online: December 16, 2014
Core Tip
Core tip: Allergen specific immuntherapy is the only therapeutic approach that can change the immunologic response to allergens and thus can alter the natural evolution of allergic diseases. Both subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) have been demonstrated to be beneficial in reducing of symptoms and drug intake,improving quality of life and preventing patients from possible side effects of high doses of steroids. This review examines the clinical effectiveness and safety of both SCIT and SLIT in patients with asthma by discussing recent studies.