Promising new treatment targets in patients with fibrosing lung disorders

doi:10.12998/wjcc.v2.i11.668

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Nov 16, 2014; 2(11): 668-675
Published online Nov 16, 2014. doi: 10.12998/wjcc.v2.i11.668

Promising new treatment targets in patients with fibrosing lung disorders

Martina Sterclova, Martina Vasakova

Martina Sterclova, Martina Vasakova, Department of Respiratory Medicine, Thomayer Hospital and 1^st Medical Faculty of Charles University, Prague 14000, Czech Republic

Author contributions: Sterclova M wrote the paper; Vasakova M critically revised the paper.

Supported by IGA Grant G 1207 (Internal Grant Agency of the Czech Ministry of Health)

Correspondence to: Martina Sterclova, MD, PhD, Department of Respiratory Medicine, Thomayer Hospital and 1^st Medical Faculty of Charles University, Videnska 800, Prague 14000, Czech Republic. martinasafrankova@seznam.cz

Telephone: +420-261-082163 Fax: +420-261-082206

Received: May 20, 2014
Revised: July 21, 2014
Accepted: September 6, 2014
Published online: November 16, 2014

Core Tip

Core tip: Novel treatment targets in patients with fibrosing interstitial lung diseases are summarized. Targets are listed according to defined cell compartments. Ongoing clinical studies focusing on some of the promising targets provide insight into current progress in lung fibrosis research.