Case Report
Copyright ©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Clin Cases. Jan 16, 2014; 2(1): 12-15
Published online Jan 16, 2014. doi: 10.12998/wjcc.v2.i1.12
Epilepsy triggered by mefloquine in an adult traveler to Uganda
Federico Gobbi, Andrea Rossanese, Dora Buonfrate, Andrea Angheben, Chiara Postiglione, Zeno Bisoffi
Federico Gobbi, Andrea Rossanese, Dora Buonfrate, Andrea Angheben, Zeno Bisoffi, Department of Tropical Diseases, Sacro Cuore-Don Calabria Hospital, 37024 Verona, Italy
Chiara Postiglione, Prevention Department, ULSS 20 Verona, 37122 Verona, Italy
Author contributions: Gobbi F wrote the manuscript; Rossanese A and Postiglione C managed the patient; Buonfrate D and Angheben A performed the literature search; Bisoffi Z revised the manuscript; all authors have read and approved the final version to be published.
Correspondence to: Federico Gobbi, MD, PhD, Department of Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Via Don A Sempreboni 5, Negrar, 37024 Verona, Italy. federico.gobbi@sacrocuore.it
Telephone: +39-45-6013563 Fax: +39-45-6013694
Received: September 25, 2013
Revised: November 7, 2013
Accepted: December 12, 2013
Published online: January 16, 2014
Core Tip

Core tip: We report a case of epilepsy due to mefloquine chemoprophylaxis. Considering that mefloquine is associated with a higher risk of neurologic and psychiatric adverse events than the alternative regimens, we suggest considering mefloquine as a second line choice after atovaquone/proguanil and doxycycline for short-term travelers.