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Méndez-Toro A. Perspectives on monitoring and diagnosis of chemotherapy-induced cardiotoxicity. World J Clin Cases 2025; 13(34): 113256 [PMID: 41377676 DOI: 10.12998/wjcc.v13.i34.113256]
Perspectives on monitoring and diagnosis of chemotherapy-induced cardiotoxicity
Arnold Méndez-Toro
Arnold Méndez-Toro, Department of Cardiology, Hospital Universitario Nacional de Colombia, Bogota 111321, Bogotá, Colombia
Author contributions: Méndez-Toro A is the sole author of this manuscript; He is responsible for the concept, intellectual content, literature search, manuscript preparation, manuscript editing, and manuscript review; He takes full responsibility for the integrity of the work as a whole and acts as the guarantor.
Conflict-of-interest statement: The author, Arnold Méndez-Toro, declares that he has no conflicts of interest, whether financial or non-financial, that could be perceived as influencing the content or conclusions of this manuscript.
Corresponding author: Arnold Méndez-Toro, Professor, Department of Cardiology, Hospital Universitario Nacional de Colombia, Cl. 44 #59-75, Bogota 111321, Bogotá, Colombia. arnold.mendez@hun.edu.co
Received: August 26, 2025 Revised: September 25, 2025 Accepted: November 17, 2025 Published online: December 6, 2025 Processing time: 104 Days and 8.3 Hours
Core Tip
Core Tip: The accurate identification and monitoring of chemotherapy-related cardiotoxicity demand inclusive patient selection and robust diagnostic strategies. Our study demonstrates that real-world cohorts often reflect local epidemiological patterns rather than exclusionary criteria, underscoring the need for comprehensive inclusion of both solid and hematologic malignancies. Retrospective designs, while valuable, may overlook subclinical conditions such as myocarditis and lack precise chemotherapy dose tracking. Integrating advanced imaging, standardized biomarker surveillance, and multicenter collaboration in prospective registries can close these gaps, enhance diagnostic certainty, and improve risk stratification. Such approaches will strengthen cardio-oncology practice and optimize long-term cardiovascular outcomes in cancer patients.
