Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2024; 12(14): 2396-2403
Published online May 16, 2024. doi: 10.12998/wjcc.v12.i14.2396
Pleomorphic rhabdomyosarcoma of the vagina: A case report
Pan Xu, Shan-Shan Ling, E Hu, Bi-Xia Yi
Pan Xu, Shan-Shan Ling, E Hu, Bi-Xia Yi, Department of Gynecology, The Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua 321000, Zhejiang Province, China
Pan Xu, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China
Co-first authors: Pan Xu and Shan-Shan Ling.
Author contributions: Xu P and Ling SS contributed equally to this work and wrote the main manuscript; Hu E prepared the figures; Xu P and Yi BX revised the final manuscript; all authors read and approved the final manuscript.
Supported by The Science and Technology Bureau Foundation of Jinhua, No. 2021-4-300 and No. 2020-3-062.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest in relation to this case report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Pan Xu, MD, Director, Department of Gynecology, The Affiliated Jinhua Hospital of Wenzhou Medical University, No. 267 Danxi East Street, Jinhua 321000, Zhejiang Province, China. xupan033@163.com
Received: January 23, 2024
Revised: February 15, 2024
Accepted: April 3, 2024
Published online: May 16, 2024
Core Tip

Core Tip: Rhabdomyosarcoma (RMS) of the vagina is an extremely rare malignant tumor in postmenopausal women. Here we describe a 68-year-old female admitted to hospital on October 11, 2023 with the chief complaint of a mass causing vaginal prolapse with incomplete urination that had persisted for 4 months. Complete resection was performed, and vaginal pleomorphic RMS was diagnosed based on pathology and immunohistochemical staining features. The patient is currently undergoing chemotherapy. This study also included review of the current literature to summarize clinical, histological, and immunohistochemical features of the postmenopausal vaginal RMS patients reported to date and latest treatment recommendations.