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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2023; 11(5): 1040-1048
Published online Feb 16, 2023. doi: 10.12998/wjcc.v11.i5.1040
Published online Feb 16, 2023. doi: 10.12998/wjcc.v11.i5.1040
Multiple regression analysis of risk factors related to radiation pneumonitis
Ling-Ling Shi, Jiang-Hua Yang, Hong-Fa Yao, Department of Radiology, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Huzhou 313000, Zhejiang Province, China
Author contributions: Shi LL conceived and designed the study; Shi LL, Yang JH, and Yao HF collected the data and performed the analysis; Shi LL was involved in the writing of the manuscript and is responsible for the integrity of the study; all authors have read and approved the final manuscript.
Institutional review board statement: The Medical Ethics Association of Huzhou Central Hospital approved the study and obtained the informed consent from all enrolled patients (approval number: HZFY-L21035478; date: August 28, 2021).
Informed consent statement: Informed consent was obtained from all enrolled patients.
Conflict-of-interest statement: All authors declare no conflict of interest for this article.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Fa Yao, BSc, Chief Technician, Department of Radiology, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, No. 1558 Sanhuan North Road, Huzhou 313000, Zhejiang Province, China. yhf817829@163.com
Received: August 30, 2022
Peer-review started: August 30, 2022
First decision: November 25, 2022
Revised: December 7, 2022
Accepted: January 20, 2023
Article in press: January 20, 2023
Published online: February 16, 2023
Peer-review started: August 30, 2022
First decision: November 25, 2022
Revised: December 7, 2022
Accepted: January 20, 2023
Article in press: January 20, 2023
Published online: February 16, 2023
Core Tip
Core Tip: Radiotherapy is a common treatment method for malignant tumors. However, it is associated with a high risk of radiation pneumonitis. Therefore, the early prevention of radiation pneumonitis is very important. We retrospectively compared medical records and analyzed the relevant clinical data of 234 patients with and without radiation pneumonitis to demonstrate that the risk factors for radiation pneumonitis include patient age, lung cancer diagnosis, history of chemotherapy, lung function, and radiotherapy parameters. Comprehensive evaluation and examination for each patient should be carried out before radiotherapy to effectively prevent radiation pneumonitis.