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Heng Y, Tang YF, Zhang XW, Duan JF, Shi J, Luo Q. Sneddon's syndrome concurrent with cerebral venous sinus thrombosis: A case report. World J Clin Cases 2023; 11(31): 7656-7662 [PMID: 38078131 DOI: 10.12998/wjcc.v11.i31.7656]
Yue Heng, Yu-Feng Tang, Xian-Wen Zhang, Jing-Feng Duan, Jian Shi, Qian Luo, Department of Neurology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang 621000, Sichuan Province, China
Author contributions: Heng Y, Luo Q, Tang YF, Zhang XW, Duan JF, and Shi J designed the research study; Heng Y and Luo Q analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Qian Luo, MD, Doctor, Department of Neurology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, No. 12 Changjia Lane, Fucheng District, Mianyang 621000, Sichuan Province, China. lqmych@163.com
Received: August 20, 2023 Peer-review started: August 20, 2023 First decision: October 10, 2023 Revised: October 13, 2023 Accepted: October 26, 2023 Article in press: October 26, 2023 Published online: November 6, 2023 Processing time: 78 Days and 1 Hours
Core Tip
Core Tip: A 26-year-old woman presented with recurrent episodes of paroxysmal unilateral limb weakness accompanied by skin mottling, seizures, and cognitive impairment. Digital subtraction angiography revealed cerebral venous sinus thrombosis (CVST). Despite negative antiphospholipid antibody results, skin biopsy indicated chronic inflammatory cell infiltration. The patient was treated using anticoagulation, antiepileptic therapy, and supportive care, which resulted in symptom improvement. The coexistence of Sneddon's syndrome (SS) and CVST is rare and the underlying pathophysiology remains uncertain. This case underscores the challenge in diagnosis and highlights the need for early clinical differentiation to facilitate accurate assessment and prompt intervention.
