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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2022; 10(31): 11381-11390
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11381
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11381
C-reactive protein as a non-linear predictor of prolonged length of intensive care unit stay after gastrointestinal cancer surgery
Ya-Min Yan, Pei-Li Jin, Jing-Jing Lu, Zheng-Hong Yu, Yan Hu, Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Jian Gao, Department of Nutrition, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Jian Gao, Center of Clinical Epidemiology and Evidence-based Medicine, Fudan University, Shanghai 200032, China
Author contributions: Hu Y and Yu ZH conceived the study and reviewed this paper; Yan YM collected data, performed this study, analyzed the data and drafted the article; Gao J participated in data collection and statistical analysis; Jin PL contributed to the training of information collectors; Lu JJ checked the quality of the collected data; All authors have read and approved this article; Yan YM and Gao J contributed equally to this work; Hu Y and Yu ZH contributed equally to this work.
Supported by Youth Program of Zhongshan Hospital , Fudan University, No. 2019ZSQN01; Fuxing Nursing Program of Fudan University , No. FNF202007 .
Institutional review board statement: The procedure mentioned conformed to the standards of the Ethics Committee on Human Experimentation of Zhongshan Hospital, Fudan University (No. B2020-107R).
Informed consent statement: Consent was obtained from the patient for publication of this study.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
Data sharing statement: The datasets generated and/or analyzed during the current study are not publicly available due to ownership by the Department of SICU, Zhongshan Hospital, Fudan University, Shanghai, China, but are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Hu, RN, Nurse, Department of Nursing, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai 200032, China. huyan10w@126.com
Received: September 9, 2022
Peer-review started: September 9, 2022
First decision: September 19, 2022
Revised: September 26, 2022
Accepted: October 9, 2022
Article in press: October 9, 2022
Published online: November 6, 2022
Peer-review started: September 9, 2022
First decision: September 19, 2022
Revised: September 26, 2022
Accepted: October 9, 2022
Article in press: October 9, 2022
Published online: November 6, 2022
Core Tip
Core Tip: Among the gastric cancer patients, C-reactive protein (CRP) levels at intensive care unit (ICU) admission were non-linearly associated with prolonged ICU length of stay (LoS) in survivors. An admission CRP level > 2.6 (log transformed mg/L) was associated with increased risk for prolonged ICU LoS.