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World J Clin Cases. Nov 6, 2022; 10(31): 11252-11259
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11252
Lactation mastitis: Promising alternative indicators for early diagnosis
Qian Huang, Xue-Mei Zheng, Mao-Lin Zhang, Ping Ning, Meng-Jun Wu
Qian Huang, Xue-Mei Zheng, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610000, Sichuan Province, China
Mao-Lin Zhang, Department of Anesthesiology, Chongqing Medical University, Chongqing 400016, Sichuan Province, China
Ping Ning, Department of Breast, Chengdu Women's and Children's Central Hospital, Chengdu 610000, Sichuan Province, China
Meng-Jun Wu, Department of Anesthesiology, Chengdu Women's and Children's Central Hospital, Chengdu 610000, Sichuan Province, China
Author contributions: Huang Q, Zheng XM and Zhang ML contributed equally to this work; Ning P, Wu MJ designed the research study; Huang Q, Zheng XM collected data from the literature; Huang Q, Zheng XM and Zhang ML wrote the manuscript; Ning P, Wu MJ conducted a review of the manuscript; all authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors have no potential conflicts of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ping Ning, MD, Doctor, Department of Breast, Chengdu Women's and Children's Central Hospital, No. 1617 Riyue Avenue, Qingyang District, Chengdu 610000, Sichuan Province, China. nping11@163.com
Received: May 9, 2022
Peer-review started: May 9, 2022
First decision: August 21, 2022
Revised: August 31, 2022
Accepted: September 22, 2022
Article in press: September 22, 2022
Published online: November 6, 2022
Core Tip

Core Tip: It has been found that milk electrolyte concentrations and electrical conductivity (EC) significantly change in the early stages of lactation mastitis (LM) in an animal model, allowing the early and specific diagnosis of LM. These indicators have not been reported in the diagnosis of LM in humans. We summarize the pathogenesis and the mechanism of LM in terms of milk electrolyte concentrations and EC and aim to provide new ideas for the early diagnosis of LM in humans.