Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 6, 2022; 10(10): 3164-3169
Published online Apr 6, 2022. doi: 10.12998/wjcc.v10.i10.3164
Endoscopic submucosal dissection combined with adjuvant chemotherapy for early-stage neuroendocrine carcinoma of the esophagus: A case report
Nan Tang, Zhen Feng
Nan Tang, Zhen Feng, Department of Gastroenterology, Shanghai Xuhui Center Hospital, Shanghai 200031, China
Author contributions: Tang N followed the patient and drafted the manuscript; Feng Z checked the data; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare no conflict of interests for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen Feng, Doctor, MD, Chief Physician, Department of Gastroenterology, Shanghai Xuhui Center Hospital, No. 966 Middle Huaihai Road, Shanghai 200031, China. fengzhen1903@hotmail.com
Received: July 17, 2021
Peer-review started: July 17, 2021
First decision: October 16, 2021
Revised: October 25, 2021
Accepted: February 22, 2022
Article in press: February 22, 2022
Published online: April 6, 2022
Core Tip

Core Tip: We describe a patient with large-cell neuroendocrine carcinoma (NEC) of the esophagus who was successfully treated using endoscopic submucosal dissection (ESD) combined with adjuvant chemotherapy. No standard treatment strategies are available for esophageal NEC due to a lack of clinical studies and its rarity. En bloc resection approach using ESD may play a vital role as a diagnostic and therapeutic modality for esophageal NEC.