Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 7, 2022; 10(1): 91-103
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.91
Value of neutrophil-lymphocyte ratio in evaluating response to percutaneous catheter drainage in patients with acute pancreatitis
Pankaj Gupta, Gaurav Chayan Das, Akash Bansal, Jayanta Samanta, Harshal S Mandavdhare, Vishal Sharma, Shano Naseem, Vikas Gupta, Thakur Deen Yadav, Usha Dutta, Neelam Varma, Manavjit Singh Sandhu, Rakesh Kochhar
Pankaj Gupta, Gaurav Chayan Das, Akash Bansal, Manavjit Singh Sandhu, Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Jayanta Samanta, Harshal S Mandavdhare, Vishal Sharma, Usha Dutta, Rakesh Kochhar, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Shano Naseem, Neelam Varma, Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Vikas Gupta, Thakur Deen Yadav, Department of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: Gupta P acquired the data, designed the outline of the paper, performed the writing and did the major revisions; Das GC and Bansal A did the majority of the writing, and prepared the figures and tables; Samanta J, Mandavdhare HS, Sharma V, Naseem S, Gupta V, Yadav TD, Dutta U, Varma N, Sandhu MS and Kochhar R contributed to data acquisition as well as to writing; all authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Postgraduate Institute of Medical Education and Research Institutional Review Board (approval No. INT/IEC/2020/SPL-468).
Informed consent statement: As this was a retrospective study, the need for informed written consent was waived.
Conflict-of-interest statement: There is no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Pankaj Gupta, MD, Associate Professor, Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. pankajgupta959@gmail.com
Received: May 13, 2021
Peer-review started: May 13, 2021
First decision: July 4, 2021
Revised: July 22, 2021
Accepted: November 26, 2021
Article in press: November 26, 2021
Published online: January 7, 2022
Core Tip

Core Tip: Predicting the success of percutaneous catheter drainage (PCD) is critical for a timely decision regarding further interventions. Neutrophilia and lymphopenia are surrogate markers of systemic inflammation and physiological stress. In this study, we evaluate the performance of white blood cell (WBC) and neutrophil-lymphocyte ratio (NLR) as predictors of response to PCD in patients with acute necrotizing pancreatitis. We found a falling trend in both WBC and NLR values, with WBC values showing a significant fall on day one after PCD compared to pre-procedure value.