Zhu JY, Yan J, Xiao J, Jia HG, Liang HJ, Xing GY. Effects of individual shock wave therapy vs celecoxib on hip pain caused by femoral head necrosis. World J Clin Cases 2023; 11(9): 1974-1984 [PMID: 36998970 DOI: 10.12998/wjcc.v11.i9.1974]
Corresponding Author of This Article
Geng-Yan Xing, PhD, Additional Professor, Orthopedic Department, The Third Medical Center of Chinese People’s Liberation Army General Hospital, The Armed Police Clinical College, Anhui Medical University, No. 81 Meishan Road, Hefei 230022, Anhui Province, China. jyzhu@ihep.ac.cn
Research Domain of This Article
Orthopedics
Article-Type of This Article
Randomized Controlled Trial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Jun-Yu Zhu, Geng-Yan Xing, Orthopedic Department, The Third Medical Center of Chinese People’s Liberation Army General Hospital, The Armed Police Clinical College, Anhui Medical University, Hefei 230022, Anhui Province, China
Jun-Yu Zhu, Jun Yan, Jian Xiao, Hai-Guang Jia, Hao-Jun Liang, Orthopedic Department, The Third Medical Center of Chinese People’s Liberation Army General Hospital, Beijing 100039, China
Author contributions: Xing GY designed this study; Yan J and Jia HG collected the data; Liang HJ analyzed the data; Zhu JY and Xiao J drafted the manuscript and gave final approval of the version to be published.
Institutional review board statement: The research protocol was approved by the Ethics Committee of The Third Medical Center of Chinese People’s Liberation Army General Hospital (ID: 001-R1).
Clinical trial registration statement: This study was registered on the Chinese Clinical Trial Registry (ChiCTR2100047844).
Informed consent statement: Informed written consent was obtained from the patients to publish this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: The datasets used and/or analyzed in the current study are available from the corresponding author upon reasonable request.
CONSORT 2010 statement: The manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Geng-Yan Xing, PhD, Additional Professor, Orthopedic Department, The Third Medical Center of Chinese People’s Liberation Army General Hospital, The Armed Police Clinical College, Anhui Medical University, No. 81 Meishan Road, Hefei 230022, Anhui Province, China. jyzhu@ihep.ac.cn
Received: November 19, 2022 Peer-review started: November 19, 2022 First decision: January 30, 2023 Revised: February 7, 2023 Accepted: March 3, 2023 Article in press: March 3, 2023 Published online: March 26, 2023
ARTICLE HIGHLIGHTS
Research background
Hip pain and functional joint limitations are the major symptoms associated with osteonecrosis of the femoral head (ONFH). The long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as celecoxib are often associated with severe adverse effects.
Research motivation
The motivation of this study was to explore a new treatment, extracorporeal shock wave therapy (ESWT) to replace pharmacotherapy in the treatment of ONFH.
Research objectives
This study investigated the efficacy of ESWT in improving pain and joint dysfunction associated with ONFH as compared to that of NSAID therapy.
Research methods
The eligible 72 ONFH patients were randomly assigned to two groups: the experiment group and the control group. All patients underwent clinical assessment and analysis during pre- and post-treatment periods.
Research results
The Harris hip score, Western Ontario and McMaster Universities Arthritis Index, and visual analog scale scores in both the experiment and control groups were significantly improved, but those of the experimental group improved to a greater degree.
Research conclusions
ESWT based on magnetic resonance imaging three-dimensional reconstruction was not inferior to celecoxib in controlling hip pain and function associated with ONFH.
Research perspectives
The findings of this study indicate that individual shock wave therapy represents an alternative to pharmacotherapy in effectively alleviating pain associated with ONFH.
