Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2020; 8(18): 4234-4244
Published online Sep 26, 2020. doi: 10.12998/wjcc.v8.i18.4234
Successful treatment of encrusted cystitis: A case report and review of literature
Jin-Gao Fu, Ke-Ji Xie
Jin-Gao Fu, Department of Urology, Jiangmen Central Hospital, Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen 529000, Guangdong Province, China
Ke-Ji Xie, Department of Urology, Guangzhou First People’s Hospital, Guangzhou 510180, Guangdong Province, China
Author contributions: Xie KJ performed the diagnostic investigations and treatments and reviewed the manuscript; Fu JG performed the literature review and wrote the manuscript; all authors have read and approved the final version of the manuscript.
Informed consent statement: This study participant provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have nothing to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ke-Ji Xie, MD, PhD, Professor, Chief Doctor, Department of Urology, Guangzhou First People's Hospital, No. 1 Panfu Road, Guangzhou 510180, Guangdong Province, China. maliaoxiekeji@sina.com
Received: June 28, 2020
Peer-review started: June 28, 2020
First decision: July 24, 2020
Revised: August 3, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: September 26, 2020
Processing time: 85 Days and 10.6 Hours
Abstract
BACKGROUND

Encrusted cystitis (EC) is a chronic inflammation of the bladder associated with mucosal encrustations. Early diagnosis and optimal treatment are not well established. Here, we report a case of EC successfully treated with com-bination therapy.

CASE SUMMARY

A 27-year-old man presented with frequency, urgency, dysuria, gross hematuria and suprapubic pain for 2 mo. He was diagnosed with EC based on characteristic calcifications of the bladder wall (most of them were struvite), cystoscopy and histopathological examination. He was cured after combined therapy of elimination of encrustations, bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into bladder submucosal tissue.

CONCLUSION

Bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into the bladder submucosal tissue can be used for treatment of EC.

Keywords: Cystitis; Encrusted cystitis; Incrusted cystitis; Hyaluronic acid; Case report; Botulinum-A neurotoxin; Botulinum toxin

Core Tip: Encrusted cystitis is a chronic inflammation of the bladder associated with mucosal encrustations. Early diagnosis and optimal treatment are not well established. We report a case of encrusted cystitis successfully treated with combined therapies of elimination of encrustations, bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into the bladder submucosal tissue. To our knowledge, we report the first description of encrusted cystitis treated with bladder instillation of hyaluronic acid and injection of botulinum-A neurotoxin into the bladder submucosal tissue.