Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2019; 7(18): 2888-2893
Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2888
Drug coated balloon angioplasty for renal artery stenosis due to Takayasu arteritis: Report of five cases
Yong-Hua Bi, Jian-Zhuang Ren, Meng-Fei Yi, Jin-Dong Li, Xin-Wei Han
Yong-Hua Bi, Jian-Zhuang Ren, Meng-Fei Yi, Xin-Wei Han, Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Jin-Dong Li, Department of Thoracic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China
Author contributions: Bi YH and Ren JZ contributed equally to this work and should be regarded as co-first authors; Bi YH, Li JD, Han XW, and Ren JZ designed the study; Bi YH, Ren JZ, and Yi MF performed the study; Bi YH and Ren JZ collected and analyzed the data; all authors wrote the paper and finally approved the version to be published.
Supported by the National Natural Science Foundation of China, No. 81501569.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Xin-Wei Han, MD, PhD, Chairman, Professor, Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Road, Zhengzhou 450052, Henan Province, China. dreamweaver08@126.com
Telephone: +86-371-66862162 Fax: +86-371-66862162
Received: April 25, 2019
Peer-review started: May 9, 2019
First decision: May 30, 2019
Revised: July 12, 2019
Accepted: July 27, 2019
Article in press: July 27, 2019
Published online: September 26, 2019
Abstract
BACKGROUND

Takayasu arteritis is a rare but intractable chronic disease in young female patients. Percutaneous transluminal angioplasty of the involved renal arteries has been reported; however, few studies have reported the use of drug coated balloon angioplasty in the treatment of Takayasu arteritis. We aimed to demonstrate five young female patients who presented with a history of hypertension due to Takayasu arteritis.

CASE SUMMARY

From April 2017 to October 2018, five female patients were diagnosed with hypertension due to Takayasu arteritis by computed tomography angiography (CTA) and laboratory tests. Four patients had a complaint of headache with or without dizziness, and one patient showed no symptom. There was no significant family or past history of hypertension or kidney disease, and the physical examinations were almost normal on admission. We performed a treatment by drug coated balloon angioplasty. Blood pressure decreased dramatically in all patients after balloon angioplasty, and the patency of treated renal artery was demonstrated with CTA over 5 months after the angioplasty procedure.

CONCLUSION

Drug coated balloon angioplasty is safe and effective for renal artery stenosis due to Takayasu arteritis. A prospective study with a larger sample size is necessary to further demonstrate the effectiveness of the treatment.

Keywords: Hypertension, Renal artery stenosis, Takayasu arteritis, Balloon angioplasty, Case report

Core tip: Percutaneous transluminal angioplasty of the involved renal arteries has been reported; however, few cases were treated by drug coated balloon angioplasty. We aimed to demonstrate five young ladies who presented with a history of hypertension due to Takayasu arteritis. Our data indicated that drug coated balloon angioplasty is safe and effective for renal artery stenosis due to Takayasu arteritis.