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Wang XP, Zheng YZ, Zhang YC. Synchronous seminal vesicle metastasis from rectosigmoid adenocarcinoma: A case report. World J Clin Cases 2026; 14(17): 121315 [DOI: 10.12998/wjcc.v14.i17.121315]
World J Clin Cases. Jun 16, 2026; 14(17): 121315 Published online Jun 16, 2026. doi: 10.12998/wjcc.v14.i17.121315
Synchronous seminal vesicle metastasis from rectosigmoid adenocarcinoma: A case report
Xin-Ping Wang, Yu-Zhu Zheng, Yuan-Chuan Zhang
Xin-Ping Wang, Yuan-Chuan Zhang, Department of General Surgery, The Affiliated Hospital of Southwest Medical University, Luzhou 646000, Sichuan Province, China
Xin-Ping Wang, Yuan-Chuan Zhang, Department of General Surgery, The Third People’s Hospital of Chengdu, Chengdu 610031, Sichuan Province, China
Yu-Zhu Zheng, Department of Oncology, The Third People’s Hospital of Chengdu, Chengdu 610031, Sichuan Province, China
Author contributions: Zhang YC and Wang XP designed the study, analyzed the data, and approved the final manuscript; Wang XP and Zhang YC followed up the patient and drafted the manuscript; Zheng YZ and Wang XP acquired the clinical and laboratory data; Zhang YC critically revised the manuscript; and all authors read and approved the final manuscript.
Supported by the Science and Technology Department of Sichuan Province, No. 2023YFS0115; and The Third People’s Hospital of Chengdu Scientific Research Project, No. 2023PI26.
Informed consent statement: Written informed consent was obtained from the patient prior to publication of this case report.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Yuan-Chuan Zhang, MD, Department of General Surgery, The Third People’s Hospital of Chengdu, No. 19 Yangshi Street, Chengdu 610031, Sichuan Province, China. chuange616@qq.com
Received: March 23, 2026 Revised: April 9, 2026 Accepted: April 28, 2026 Published online: June 16, 2026 Processing time: 74 Days and 16 Hours
Abstract
BACKGROUND
Seminal vesicle metastasis from colorectal cancer (CRC) is extremely rare and poses diagnostic and therapeutic challenges. Limited cases have been reported, and its clinical characteristics remain poorly understood.
CASE SUMMARY
We report a case of synchronous seminal vesicle metastasis originating from rectosigmoid adenocarcinoma. The diagnosis was established through imaging and confirmed by histopathology. The patient underwent surgical resection followed by adjuvant chemotherapy and achieved favorable outcomes with no evidence of recurrence during a two-year follow-up period.
CONCLUSION
Seminal vesicle metastasis should be considered in atypical cases of CRC.
Core Tip: Seminal vesicle metastasis from colorectal cancer is extremely rare and difficult to diagnose. We report a case of synchronous metastasis from rectosigmoid adenocarcinoma confirmed by imaging and histopathology, with favorable long-term outcomes. This case highlights the importance of distinguishing distant metastasis from direct invasion and supports comprehensive treatment strategies.
