Letter to the Editor
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 16, 2023; 11(2): 479-481
Published online Jan 16, 2023. doi: 10.12998/wjcc.v11.i2.479
Incidence and clinical treatment of hypertriglyceridemic acute pancreatitis: A few issues
Qun-Ying Yang, Qian Zhao, Jian-Wen Hu
Qun-Ying Yang, Qian Zhao, Jian-Wen Hu, Department of Gastroenterology, Dongyang People's Hospital, Dongyang 322100, Zhejiang Province, China
Author contributions: Yang QY and Zhao Q reviewed the literature and contributed to manuscript drafting; Hu JW was responsible for the revision of the manuscript for important intellectual content; All authors reviewed and approved the final version.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Wen Hu, PhD, Professor, Department of Gastroenterology, Dongyang People's Hospital, No. 60 Wuning West Road, Dongyang 322100, Zhejiang Province, China. cchcsq0529@163.com
Received: September 22, 2022
Peer-review started: September 22, 2022
First decision: November 5, 2022
Revised: November 16, 2022
Accepted: January 3, 2023
Article in press: January 3, 2023
Published online: January 16, 2023

Hypertriglyceridemia is a well-recognized etiology of acute pancreatitis, and the incidence of hypertriglyceridemic acute pancreatitis (HTG-AP) has increased in frequency worldwide in response to lifestyle changes. It is crucial to identify hypertriglyceridemia as the cause of pancreatitis and initiate appropriate treatment. Insulin treatment produces effective lowering of triglycerides, but in our opinion, non-diabetic patients with HTG-AP require separate consideration to avoid hypoglycemia.

Keywords: Hypertriglyceridemic acute pancreatitis, Incidence, Etiology, Insulin, Treatment

Core Tip: This is a comment on an article concerning the incidence and clinical characteristics of hypertriglyceridemic acute pancreatitis (HTG-AP). We believe that the risk of hypoglycemia must be considered and described for non-diabetic patients with HTG-AP receiving insulin infusion to decrease serum triglyceride level.