Su YQ, Liu ZY, Wei G, Zhang CM. Topical halometasone cream combined with fire needle pre-treatment for treatment of primary cutaneous amyloidosis: Two case reports. World J Clin Cases 2022; 10(20): 7147-7152 [PMID: 36051117 DOI: 10.12998/wjcc.v10.i20.7147]
Corresponding Author of This Article
Chun-Min Zhang, MD, Chief Doctor, Department of Dermato-venereology, The Second Hospital of Shandong University, No. 247 Beiyuan Street, Jinan 250000, Shandong Province, China. cmzhang1878@163.com
Research Domain of This Article
Dermatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jul 16, 2022; 10(20): 7147-7152 Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.7147
Topical halometasone cream combined with fire needle pre-treatment for treatment of primary cutaneous amyloidosis: Two case reports
Yan-Qian Su, Zhao-Yang Liu, Guo Wei, Chun-Min Zhang
Yan-Qian Su, Zhao-Yang Liu, Guo Wei, Chun-Min Zhang, Department of Dermato-venereology, The Second Hospital of Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Su YQ was the patient’s dermatologist, reviewed the literature, and contributed to manuscript drafting; Liu ZY reviewed the literature and contributed to manuscript drafting; Zhang CM and Wei G was responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported bythe Shandong Scientific Technology Program, No. 2015GSF118003; and the Jinan Science and Technology Plan Projects, No. 201503019.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Min Zhang, MD, Chief Doctor, Department of Dermato-venereology, The Second Hospital of Shandong University, No. 247 Beiyuan Street, Jinan 250000, Shandong Province, China. cmzhang1878@163.com
Received: January 11, 2022 Peer-review started: January 11, 2022 First decision: March 15, 2022 Revised: March 27, 2022 Accepted: May 28, 2022 Article in press: May 28, 2022 Published online: July 16, 2022
Abstract
BACKGROUND
Primary cutaneous amyloidosis (PCA) is a chronic metabolic skin disease that has a detrimental impact on physical and mental health. It appears as mossy papules and severe itching, which is long-term and recurrent. Traditional treatments are unsatisfactory, especially for refractory cases. Fire needle therapy, which is widely used in China, has shown good clinical efficacy, as well as advantages concerning safety and cost. Clinical reports about fire needle treatment of this disease are few at present.
CASE SUMMARY
We report two older men who had developed maculopapules with itchiness on the trunk and arms for more than 10-15 years. Due to the dermatopathological findings, PCA was our primary consideration. They received topical halometasone cream and pretreatment with fire needle for 8-16 wk. Both patients showed significant improvement of lesions. Neither patient had recurrence with a minimum of 2 years of follow-up.
CONCLUSION
Topical halometasone cream and pretreatment with fire needle could be a fast, safe, and economic treatment for PCA.
Core Tip: We explored a combination therapy for primary cutaneous amyloidosis, which is fast and noninvasive with low recurrence. The effects of topical drugs could be more pronounced after fire needle intervention. Topical halometasone cream plus fire needle pre-treatment could shorten the course of treatment and reduce recurrence.
