Liang M, Li LD, Li L, Li S. Nanotechnology in diagnosis and therapy of gastrointestinal cancer. World J Clin Cases 2022; 10(16): 5146-5155 [PMID: 35812681 DOI: 10.12998/wjcc.v10.i16.5146]
Corresponding Author of This Article
Shuo Li, MD, Chief Physician, Department of Otolaryngology, Huazhong University of Science and Technology Union Shenzhen Hospital, The sixth Affiliated Hospital of Shenzhen University Health Science Center, No. 89 Taoyuan Avenue, Shenzhen 518053, Guangdong Province, China. shuoli@email.szu.edu.cn
Research Domain of This Article
Nanoscience & Nanotechnology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jun 6, 2022; 10(16): 5146-5155 Published online Jun 6, 2022. doi: 10.12998/wjcc.v10.i16.5146
Nanotechnology in diagnosis and therapy of gastrointestinal cancer
Meng Liang, Li-Dan Li, Liang Li, Shuo Li
Meng Liang, Shuo Li, Department of Otolaryngology, Huazhong University of Science and Technology Union Shenzhen Hospital, The sixth Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen 518053, Guangdong Province, China
Li-Dan Li, National Clinical Research Center for Infectious Diseases, Shenzhen Third People's Hospital, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen 518112, Guangdong Province, China
Liang Li, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518059, Guangdong Province, China
Author contributions: Liang M and Li LD performed the majority of the writing, prepared the figures and tables; Li L and Li S designed the outline and coordinated the writing of the paper.
Supported bythe Nanshan District Science and Technology Plan Project, No. 2020048 General; and the Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties, No. SZGSP010.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shuo Li, MD, Chief Physician, Department of Otolaryngology, Huazhong University of Science and Technology Union Shenzhen Hospital, The sixth Affiliated Hospital of Shenzhen University Health Science Center, No. 89 Taoyuan Avenue, Shenzhen 518053, Guangdong Province, China. shuoli@email.szu.edu.cn
Received: November 16, 2021 Peer-review started: November 16, 2021 First decision: December 27, 2021 Revised: January 7, 2022 Accepted: April 3, 2022 Article in press: April 3, 2022 Published online: June 6, 2022
Abstract
Advances in nanotechnology have opened new frontiers in the diagnosis and treatment of cancer. Nanoparticle-based technology improves the precision of tumor diagnosis when combined with imaging, as well as the accuracy of drug target delivery, with fewer side effects. Optimized nanosystems have demonstrated advantages in many fields, including enhanced specificity of detection, reduced toxicity of drugs, enhanced effect of contrast agents, and advanced diagnosis and therapy of gastrointestinal (GI) cancers. In this review, we summarize the current nanotechnologies in diagnosis and treatment of GI cancers. The development of nanotechnology will lead to personalized approaches for early diagnosis and treatment of GI cancers.
Core Tip: The aim of this review is to summarize nanotechnologies in gastrointestinal (GI) cancer diagnosis and therapy. Nanodevices have the advantages of enhancing the specificity of detection and reducing toxicity of drugs in diagnosis and treatment of GI cancers.
