El-Khashab SO, Mohamed EES, Soliman MA, Kassem HH, Soliman AR. Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults. World J Nephrol 2016; 5(6): 517-523 [PMID: 27872833 DOI: 10.5527/wjn.v5.i6.517]
Corresponding Author of This Article
Amin Roshdy Soliman, MD, PhD, FASN, Professor of Medicine and Nephrology, Department of Nephrology, Kasr Al-Ainy Cairo University, 41 Manial street, Cairo 11451, Egypt. aminroshdy@yahoo.com
Research Domain of This Article
Transplantation
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
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World J Nephrol. Nov 6, 2016; 5(6): 517-523 Published online Nov 6, 2016. doi: 10.5527/wjn.v5.i6.517
Table 1 Demographic and laboratory data of various groups (mean values)
Age in years
Male/female
BMI (kg/m2)
Hb pre Tx
Creatinine ne post Tx (mg/dL)
Hb post Tx (g/dL)
Duration of dialysis in years
Group 1
9.8 ± 3.7
18/12
25.8 ± 4.4
6.9 ± 1.0
0.9 ± 0.3
13.9 ± 0.9
0.6 ± 0.2
Group 2
26.8 ± 5.6
25/5
24.7 ± 3.1
6.9 ± 1.2
1.2 ± 0.2
13.3 ± 1.9
0.9 ± 0.4
Group 3
10.7 ± 2.4
12/8
28.2 ± 9.0
8.7 ± 1.5
3.3 ± 1.2
Group 4
43.9 ± 14.1
8/12
22.7 ± 5.2
9.7 ± 1.9
8.5 ± 4.7
Group 5
12.0 ± 1.5
5 males
18.0 ± 1.5
14.2 ± 0.8
Group 6
30.2 ± 3.7
5 males
25.7 ± 3.8
13.2 ± 1.3
Table 2 Echocardiographic data in various groups (mean values)
LVED pre Tx
LVES pre Tx
FS pre Tx
EF pre Tx
LVED post Tx
LVES post Tx
FS post Tx
EF post Tx
Group 1
4.7 ± 0.8
3.1 mm ± 0.6 mm
32.6% ± 5.3%
59.7% ± 7.0%
4.2 mm ± 0.5 mm
2.4 mm ± 0.4 mm
41.7% ± 7.6%
71.9 ± 6.1
Group 2
5.9 ± 0.7
4.1 ± 0.9
29.0 ± 6.6
52.0 ± 12.5
4.9 ± 0.6
3.1 ± 0.5
36.5 ± 4.1
64.8 ± 5.9
Group 3
4.7 ± 0.8
3.2 ± 0.6
30.9 ± 5.0
56.5 ± 6.3
Group 4
5.6 ± 0.8
4.0 ± 1.0
29.2 ± 4.3
50.2 ± 7.4
Group 5
4.2 ± 0.4
LVES 3.0 ± 0.5
41.9 ± 2.3
71.6 ± 4.0
Group 6
5.0 ± 0.3
3.1 ± 0.6
38.0 ± 1.9
64.8 ± 3.4
Table 3 Comparison of children data before and after renal transplantation
Variables
Before renal transplantation(mean ± SD)
After renal transplantation(mean ± SD)
P-value(P-value is significant if < 0.05)
Hemoglobin n (g/dL)
6.9 ± 1.0
13.9 ± 0.9
0.0001
LVED (mm)
4.7 ± 0.8
4.2 ± 0.5
0.0001
LVES (mm)
3.1 ± 0.6
2.4 ± 0.4
0.0001
FS (%)
32.6 ± 5.3
41.7 ± 7.6
0.0001
EF (%)
59.7 ± 7.0
71.9 ± 6.1
0.0001
Table 4 Comparison of adults’ data before and after renal transplantation
Variables
Before renal transplantation(mean ± SD)
After renal transplantation(mean ± SD)
P-value(P-value is significant if < 0.05)
Hemoglobin (g/dL)
6.9 ± 1.2
13.3 ± 1.9
0.0001
LVED (mm)
5.9 ± 0.7
4.9 ± 0.6
0.0001
LVES (mm)
4.1 ± 0.9
3.1 ± 0.5
0.0001
FS (%)
29.0 ± 6.6
36.5 ± 4.1
0.0001
EF (%)
52.0 ± 12.5
64.8 ± 5.9
0.0001
Citation: El-Khashab SO, Mohamed EES, Soliman MA, Kassem HH, Soliman AR. Impact of renal transplantation on cardiac morphological and functional characteristics in children and adults. World J Nephrol 2016; 5(6): 517-523