Review
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World J Nephrol. Nov 6, 2014; 3(4): 169-181
Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.169
Preeclampsia from a renal point of view: Insides into disease models, biomarkers and therapy
Janina Müller-Deile, Mario Schiffer
Janina Müller-Deile, Mario Schiffer, Division of Nephrology and Hypertension, Department of Medicine, Hannover Medical School, 30625 Hannover, Germany
Author contributions: Müller-Deile J and Schiffer M solely contributed to this paper.
Correspondence to: Janina Müller-Deile, MD, Division of Nephrology and Hypertension, Department of Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. schiffer.mario@mh-hannover.de
Telephone: +49-51-15324708 Fax: +49-51-1552366
Received: March 20, 2014
Revised: August 6, 2014
Accepted: September 4, 2014
Published online: November 6, 2014
Core Tip

Core tip: This review summarises different pathophysiological theories of preeclampsia with a special focus on the renal facets of the disease. In this context current animal models are presented. The reader gets a broad overview about different biomarkers for preeclampsia. Furthermore, the article discusses treatment options for preeclampsia related symptoms including the use of plasmapheresis as a rescue therapy for so far refractory preeclampsia.