Review
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World J Nephrol. Nov 6, 2014; 3(4): 182-192
Published online Nov 6, 2014. doi: 10.5527/wjn.v3.i4.182
Acute kidney injury due to bilateral ureteral obstruction in children
Daniele Bianchi, Giuseppe Vespasiani, Pierluigi Bove
Daniele Bianchi, Giuseppe Vespasiani, Pierluigi Bove, Department of Urology, Policlinico Tor Vergata, Viale Oxford, 00100 Rome, Italy
Author contributions: All authors contributed to the manuscript.
Correspondence to: Daniele Bianchi, MD, Department of Urology, Policlinico Tor Vergata, Viale Oxford, 81, 00100 Rome, Italy. danielebianchimail@yahoo.it
Telephone: +39-62-0902977 Fax: +39-62-0902975
Received: June 29, 2014
Revised: July 28, 2014
Accepted: September 4, 2014
Published online: November 6, 2014
Processing time: 130 Days and 21.6 Hours
Abstract

Bilateral ureteral obstruction in children is a rare condition arising from several medical or surgical pictures. It needs to be promptly suspected in order to attempt a quick renal function recovery. In this paper we concentrated on uncommon causes of obstruction, with the aim of giving a summary of such multiple, rare and heterogeneous conditions joint together by the common denominator of sudden bilateral ureteral obstruction, difficult to be suspected at times. Conversely, typical and well-known diseases have been just run over. We considered pediatric cases of ureteral obstruction presenting as bilateral, along with some cases which truly appeared as single-sided, because of their potential bilateral presentation. We performed a review of the literature by a search on PubMed, CrossRef Metadata Search, internet and reference lists of single articles updated to May 2014, with no time limits in the past. Given that we deal with rare conditions, we decided to include also papers in non-English languages, published with an English abstract. For the sake of clearness, we divided our research results into 8 categories: (1) urolithiasis; (2) congenital urinary tract malformations; (3) immuno-rheumatologic causes of ureteral obstruction; (4) ureteral localization of infections; (5) other systemic infective causes of ureteral obstructions; (6) neoplastic intrinsic ureteral obstructions; (7) extrinsic ureteral obstructions; and (8) iatrogenic trigonal obstruction or inflammation. Of course, different pathogenic mechanisms underlay those clinical pictures, partly well-known and partly not completely understood.

Keywords: Acute kidney injury; Bilateral ureteral obstruction; Hydronephrosis; Anuria; Pediatrics; Ureteral stenting; Henoch-Schönlein purpura; Tuberculosis; Masses; Congenital malformations

Core tip: Bilateral ureteral obstruction in children is a rare condition related to several medical or surgical pictures. It needs to be promptly suspected in order to attempt a quick renal function recovery. It is a rare event, but to be kept in mind. We identified many potential causes grouped as follows: (1) urolithiasis; (2) congenital urinary tract malformations; (3) immuno-rheumatologic causes of ureteral obstruction; (4) ureteral localization of infections; (5) other systemic infective causes of ureteral obstruction; (6) neoplastic intrinsic ureteral obstructions; (7) extrinsic ureteral obstructions; and (8) iatrogenic trigonal obstruction or inflammation.