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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Nov 25, 2021; 10(6): 301-311
Published online Nov 25, 2021. doi: 10.5501/wjv.v10.i6.301
Published online Nov 25, 2021. doi: 10.5501/wjv.v10.i6.301
Impact of COVID-19 on liver disease: From the experimental to the clinic perspective
Sheila Gato, Rocío Muñoz-Hernández, Manuel Romero-Gómez, Javier Ampuero, SeLiver Group, Instituto de Biomedicina de Sevilla, Sevilla 41013, Spain
Ana Lucena-Valera, José Manuel Sousa, Manuel Romero-Gómez, Javier Ampuero, Digestive Department, Hospital Universitario Virgen del Rocio, Sevilla 41013, Spain
Rocío Muñoz-Hernández, Manuel Romero-Gómez, Javier Ampuero, University of Seville, Sevilla 41013, Spain
Author contributions: Ampuero J conceived and designed the review; Muñoz-Hernández R, and Sousa JM collected data from the literature; Gato S, and Lucena-Valera A drafted the manuscript; Ampuero J and Romero-Gómez MR critically revised the manuscript.
Conflict-of-interest statement: No conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Javier Ampuero, MD, MSc, PhD, Doctor, Professor, Senior Scientist, Digestive Department, Hospital Universitario Virgen del Rocio, Avda. Manuel Siurot s/n, Sevilla 41013, Spain. javi.ampuero@gmail.com
Received: March 24, 2021
Peer-review started: March 24, 2021
First decision: May 5, 2021
Revised: May 18, 2021
Accepted: August 13, 2021
Article in press: August 13, 2021
Published online: November 25, 2021
Peer-review started: March 24, 2021
First decision: May 5, 2021
Revised: May 18, 2021
Accepted: August 13, 2021
Article in press: August 13, 2021
Published online: November 25, 2021
Core Tip
Core Tip: The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a critical threat to global public health. Beyond the respiratory symptoms, some patients with COVID-19 show liver damage. In this scenario, it has been suggested that there might be a specific relationship between SARS-CoV-2 infection and liver injury.