Published online Nov 12, 2014. doi: 10.5499/wjr.v4.i3.35
Revised: August 18, 2014
Accepted: September 18, 2014
Published online: November 12, 2014
Core tip: In comparison to men, women with ankylosing spondylitis (AS) experience a higher subjective burden of disease despite lower objective signs of systemic inflammation and less spinal radiographic damage. A better response to treatment with tumor necrosis factor inhibitors has been demonstrated in male AS patients.