Published online Nov 12, 2013. doi: 10.5499/wjr.v3.i3.32
Revised: September 30, 2013
Accepted: November 1, 2013
Published online: November 12, 2013
Core tip: Systemic lupus erythematosus (SLE) typically affects women in their childbearing age. The effect of pregnancy on the disease and the effect of SLE on pregnancy and the fetus are highly important issues for the attending physician. The newborn may be affected by the onset of neonatal lupus erythematosus, either as a skin or blood disease, or by the presence of congenital heart block. The frequent association between SLE and antiphospholipid syndrome represents another risk situation. Optimization of pharmacological therapy before and during pregnancy should be done in order to reduce adverse events to the mother and the baby.