Olfactory function in psychotic disorders: Insights from neuroimaging studies

Figure 1 Neural activation for passive smelling in controls-patients. For both locations (thalamus and right orbitofrontal), controls showed significant activation relative to psychosis patients that was unrelated to sex. A: Thalamus; B: Right orbitofrontal. From Good et al (under review).

Figure 2 Figure showing difference between hedonic processing and baseline (air) for patients with psychotic disorders and control subjects. Differences in activation were noted between patients and control subjects in anterior insula and inferior frontal gyrus. Controls had enhanced activation in both sites for the hedonicity condition (relative to baseline) while for the anterior insula, patients showed no increase and for inferior frontal regions patients saw a statistically significant decrease in regional cerebral blood flow (H-B). Reprinted with permission from Plailly et al[25]. ^aP < 0.05, ^bP < 0.001.