Disease duration-stratified associations of thyroid hormone levels with psychopathology in hospitalized patients with schizophrenia: A cross-sectional study

doi:10.5498/wjp.v15.i9.109858

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Sep 19, 2025; 15(9): 109858
Published online Sep 19, 2025. doi: 10.5498/wjp.v15.i9.109858

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Figure 1 Box plots of intergroup comparisons of thyroid hormone concentrations between groups with different disease duration. ^aP < 0.017. A: Triiodothyronine concentrations; B: Free triiodothyronine concentrations; C: Thyroxine concentrations; D: Free thyroxine concentrations; E: Thyroid stimulating hormone concentrations, each compared across the three groups. TSH: Thyroid stimulating hormone; T3: Triiodothyronine; FT3: Free triiodothyronine; T4: Thyroxine; FT4: Free thyroxine.

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Figure 2 Scatter plots of thyroid hormone levels vs Positive and Negative Syndrome Scale subscale scores, showing unadjusted data and standardized residuals. A: Triiodothyronine (T3): Unadjusted; B: T3: Standardized residuals; C: Thyroxine (T4): Unadjusted; D: T4: Standardized residuals; E: Free T3: Unadjusted; F: Free T3: Standardized residuals; G: Free T4: Unadjusted; H: Free T4: Standardized residuals; I: Thyroid stimulating hormone: Unadjusted; J: Thyroid stimulating hormone: Standardized residuals. TSH: Thyroid stimulating hormone; T3: Triiodothyronine; FT3: Free triiodothyronine; T4: Thyroxine; FT4: Free thyroxine; PANSS: Positive and Negative Syndrome Scale.

Citation: Lei XP, Liao DX, Wu GY, Shuai D, Zhang HL, Wang BY, Wang YL. Disease duration-stratified associations of thyroid hormone levels with psychopathology in hospitalized patients with schizophrenia: A cross-sectional study. World J Psychiatry 2025; 15(9): 109858
URL: https://www.wjgnet.com/2220-3206/full/v15/i9/109858.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i9.109858