Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression

Figure 1 White matter regions with significant differences in fractional amplitude of low frequency fluctuations, regional homogeneity and independent component analysis in adolescents with major depression disorders compared to healthy controls. Maps a threshold at P < 0.001, FWE voxel correction. fALFF: Fractional amplitude of low frequency fluctuations; WM: White matter; ReHo: Regional homogeneity; ICA: Independent component analysis; L: Left; R: Right; MDD: Major depression disorders.

Figure 2 Correlations between clinical psychiatric symptoms and white matter regions with significant differences in the major depression disorders and healthy controls groups. A: It is a significant brain region left posterior limb of internal capsule in fractional amplitude of low frequency fluctuations (fALFF) of white matter (WM); B: It is a significant brain region right posterior corona radiata in fALFF of WM. MINISS: The mini international neuropsychiatric interview suicidality subscale.