Copyright ©The Author(s) 2022.
World J Psychiatry. Jan 19, 2022; 12(1): 24-58
Published online Jan 19, 2022. doi: 10.5498/wjp.v12.i1.24
Figure 1
Figure 1 Results from the search “resilience and addiction” in the PubMed database (, accessed on December 15, 2021). Number of papers published each year from 2000 until 2020.
Figure 2
Figure 2 Simplified diagram of the neurobiological substrates of resilience to the effects of social defeat in rodents. Resilience is induced by activation of the pathways indicated with gross lines and by inhibition or normalization of the pathways represented with dashed lines. LC: Locus coeruleus; VTA: Ventral tegmental area; PFC: Prefrontal cortex; NAcc: Nucleus accumbens; vHipp: Ventral hippocampus; Amyg: Amygdala.