Case Report
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Jun 22, 2017; 7(2): 128-132
Published online Jun 22, 2017. doi: 10.5498/wjp.v7.i2.128
Cognitive correlates of neuroimaging abnormalities in the onset of schizophrenia: A case report
Silvia Grassi, Giulia Orsenigo, Marta Serati, Elisabetta Caletti, Alfredo Carlo Altamura, Massimiliano Buoli
Silvia Grassi, Giulia Orsenigo, Marta Serati, Elisabetta Caletti, Alfredo Carlo Altamura, Massimiliano Buoli, Department of Psychiatry, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, 20122 Milan, Italy
Author contributions: Grassi S and Orsenigo G collected data; Serati M revised report; Caletti E performed neuropsychological tests; Altamura AC designed the report; Buoli M wrote the paper.
Institutional review board statement: This case report was exempted from IRB standards of University of Milan.
Informed consent statement: Patient gave his written informed consent and permission for disclosure of his protected health information.
Conflict-of-interest statement: Professor Altamura has served as a consultant or on Advisory Boards for Roche, Merck, Astra Zeneca, Bristol Myers Squibb, Janssen/Cilag and Lundbeck. Drs Grassi, Orsenigo, Serati, Caletti and Buoli do not have any affiliation with or financial interest in any organization that might pose a conflict of interest with the present article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Silvia Grassi, MD, Department of Psychiatry, University of Milan, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Via F. Sforza 35, 20122 Milan, Italy. silvia.grassi1@unimi.it
Telephone: +39-02-55035983 Fax: +39-02-55033190
Received: December 17, 2016
Peer-review started: December 19, 2016
First decision: April 18, 2017
Revised: April 27, 2017
Accepted: May 12, 2017
Article in press: May 15, 2017
Published online: June 22, 2017
Core Tip

Core tip: Schizophrenia is associated with impairment in executive function, verbal memory, verbal fluency and attention. Neuropsychological tests are associated with structural and functional brain alterations. This case report is an example of the potential correlation between clinical symptoms (e.g., cognitive impairment) and brain changes. These data may help in the prediction of possible outcome of schizophrenia patients.