Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Dec 22, 2016; 6(4): 399-409
Published online Dec 22, 2016. doi: 10.5498/wjp.v6.i4.399
Treatment-adherence in bipolar disorder: A patient-centred approach
Subho Chakrabarti
Subho Chakrabarti, Department of Psychiatry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India
Author contributions: Chakrabarti S solely contributed to this paper.
Conflict-of-interest statement: No conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Subho Chakrabarti, MD, FAMS, FRCPsych, Professor, Department of Psychiatry, Postgraduate Institute of Medical Education and Research (PGIMER), Sector-12, Chandigarh 160012, India.
Telephone: +91-172-2756808 Fax: +91-172-2744401
Received: August 17, 2016
Peer-review started: August 19, 2016
First decision: October 21, 2016
Revised: October 31, 2016
Accepted: November 21, 2016
Article in press: November 22, 2016
Published online: December 22, 2016
Core Tip

Core tip: Treatment non-adherence in bipolar disorder (BD) is a complex phenomenon determined by a multitude of influences, but its critical determinants are yet to be identified with certainty. Demographic and illness-related factors have not been able to explain or predict non-adherence in BD. On the other hand, patient-centred variables such as attitudes and beliefs regarding medications, treatment-alliance, family attitudes, knowledge, stigma and access to treatment may be the more seminal influences on medication-taking in BD. A move from an illness-centred to a patient-centred approach is more likely to lead to a better understanding and more effective solutions for non-adherence in BD.