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World J Psychiatry. Sep 19, 2026; 16(9): 120368
Published online Sep 19, 2026. doi: 10.5498/wjp.120368
Published online Sep 19, 2026. doi: 10.5498/wjp.120368
Screening and analysis of influencing factors for comorbidity of chronic glaucoma with depression and anxiety
Jun Chen, Sha-Sha Wang, Ting-Ting Wang, Anhui Eye Hospital, Anhui No. 2 Provincial People’s Hospital, Hefei 230041, Anhui Province, China
Yang Li, Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Chen J was responsible for conceptualization, methodology, formal analysis, writing – original draft, writing – review and editing, visualization, project administration; Wang SS was responsible for data curation, investigation, validation, writing – review and editing; Wang TT was responsible for software, formal analysis, visualization, writing – review and editing; Li Y was responsible for supervision, methodology, resources, writing – review and editing, funding acquisition; all of the authors read and approved the final version of the manuscript to be published.
AI contribution statement: No AI tools were used in the preparation of this manuscript.
Institutional review board statement: The study was approved by the Medical Ethics Committee of Anhui No. 2 Provincial People’s Hospital, approval No. (R) 2026-015.
Informed consent statement: All participants provided informed consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: Data are available from the corresponding author upon reasonable request.
Corresponding author: Yang Li, Chief Pharmacist, Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230022, Anhui Province, China. lycjlzq@163.com
Received: March 13, 2026
Revised: April 9, 2026
Accepted: June 3, 2026
Published online: September 19, 2026
Processing time: 163 Days and 21.8 Hours
Revised: April 9, 2026
Accepted: June 3, 2026
Published online: September 19, 2026
Processing time: 163 Days and 21.8 Hours
Core Tip
Core Tip: This analysis of 220 chronic glaucoma patients identified a 27.73% comorbidity rate of depression and anxiety. Longer disease duration, more severe visual field defects, and lower monthly family income were independent risk factors. It is therefore necessary to carry out psychological assessments and implement multi-dimensional interventions for this patient group.