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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jul 19, 2025; 15(7): 103684
Published online Jul 19, 2025. doi: 10.5498/wjp.v15.i7.103684
Published online Jul 19, 2025. doi: 10.5498/wjp.v15.i7.103684
Effects of combined preconception and prenatal myo-inositol, probiotics, and trace element supplementation on the outcomes of depressed mothers
Shu-Fang Qi, Jie Zhao, Department of Medical Genetics and Prenatal Diagnosis, The Second Children and Women’s Healthcare of Jinan City, Jinan 271100, Shandong Province, China
Hong-Xia Sun, Operating Room, The Second Children and Women’s Healthcare of Jinan City, Jinan 271100, Shandong Province, China
Author contributions: Qi SF and Zhao J designed the experiments, conducted clinical data collection, conducted the collation and statistical analysis, wrote the original manuscript, and revised the paper; Sun HX performed postoperative follow-up and recorded the data; All authors read and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Second Children and Women’s Healthcare of Jinan City.
Informed consent statement: The ethics committee agreed to waive informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Zhao, Department of Medical Genetics and Prenatal Diagnosis, The Second Children and Women’s Healthcare of Jinan City, No. 12 Fengcheng West Street, Laiwu District, Jinan 271100, Shandong Province, China. lwfbyzhj8900@163.com
Received: March 7, 2025
Revised: April 21, 2025
Accepted: June 4, 2025
Published online: July 19, 2025
Processing time: 124 Days and 20 Hours
Revised: April 21, 2025
Accepted: June 4, 2025
Published online: July 19, 2025
Processing time: 124 Days and 20 Hours
Core Tip
Core Tip: This study assessed the effects of combined myo-inositol, probiotics, and trace elements on maternal and fetal health. Results showed reduced gestational diabetes mellitus and hypertension rates, improved postpartum mood, and enhanced quality of life scores. Fetal growth parameters and neonatal outcomes also improved. These findings highlight a promising strategy to reduce complications and improve maternal-fetal health.