Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jun 19, 2025; 15(6): 105334
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.105334
Correlation of anxiety and depression with pain in patients with diabetic foot ulcers and analysis of risk factors
Jiang-Qiang Chen, Zu-Hui Chen, Wei-Bin Zheng, Xiang-Qian Shen
Jiang-Qiang Chen, Zu-Hui Chen, Wei-Bin Zheng, Department of Plastic Surgery, Tiantai County People’s Hospital, Taizhou 317200, Zhejiang Province, China
Xiang-Qian Shen, Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China
Author contributions: Chen JQ designed the study, collected and analyzed the data, and wrote the manuscript; Chen JQ, Chen ZH, and Zheng WB participated in the study conception and data collection; Chen JQ and Shen XQ contributed to the study design and provided guidance; All authors read and approved the final version of the manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of Tiantai County People’s Hospital.
Informed consent statement: Patients were not required to provide informed consent for the study, because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang-Qian Shen, PhD, Doctor, Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 1367 Wenyi West Road, Yuhang District, Hangzhou 310003, Zhejiang Province, China. shenxiangqian@sina.com
Received: February 18, 2025
Revised: March 24, 2025
Accepted: April 27, 2025
Published online: June 19, 2025
Processing time: 100 Days and 1.2 Hours
Core Tip

Core Tip: Studies on the correlation between anxiety, depression, and pain in diabetic foot ulcers (DFUs) and analysis of contributing risk factors are limited. This study addresses this gap by providing valuable clinical insights. The findings demonstrate a significant positive correlation between anxiety, depression, and pain in patients with DFUs, highlighting the importance of timely and effective pain management in mitigating these negative emotional states. Furthermore, younger age (< 50 years), higher Wagner’s grade, and high visual analog scale scores were identified as key risk factors for anxiety and depression. Targeted psychological support and proactive interventions for patients exhibiting these characteristics, such as age < 50 years, advanced Wagner’s grades, or high pain levels, can effectively minimize their susceptibility to anxiety and depression.