Risk factors for anxiety and depression in patients with atopic dermatitis and their impact on prognosis

doi:10.5498/wjp.v15.i6.104738

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Jun 19, 2025 (publication date) through May 29, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Jun 19, 2025; 15(6): 104738
Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.104738

Risk factors for anxiety and depression in patients with atopic dermatitis and their impact on prognosis

Kun Liu, Wei Gao, Hong-Guang Lu, Zhao-Gui Chen

Kun Liu, Wei Gao, Department of Dermatology, Shanghai Jinshan Tinglin Hospital, Shanghai 200444, China

Hong-Guang Lu, Department of Dermatology, Affiliated Hospital of Guizhou Medical University, Guiyang 550000, Guizhou Province, China

Zhao-Gui Chen, Department of Psychiatry, The Fourth People’s Hospital of Yulin, Yulin 537000, Guangxi Zhuang Autonomous Region, China

Author contributions: Liu K designed the study; Gao W and Lu HG analyzed the data; Liu K was involved in the data collection and writing of this article; All authors read and approved the final manuscript.

Institutional review board statement: This study was approved by the Ethics Committee of the Shanghai Jinshan Tinglin Hospital (No. SHRJ24141110).

Informed consent statement: All study participants and their legal guardians provided written informed consent before enrolment.

Conflict-of-interest statement: The authors declare that they have no conflicts of interest.

Data sharing statement: No additional data are available.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Kun Liu, PhD, Doctor, Department of Dermatology, Shanghai Jinshan Tinglin Hospital, No. Siping North Road, Tinglin Town,Jinshan District Shanghai 201505, China. lkk13661609261@126.com

Received: March 19, 2025
Revised: April 14, 2025
Accepted: May 7, 2025
Published online: June 19, 2025
Processing time: 71 Days and 1.1 Hours

Core Tip

Core Tip: Atopic dermatitis (AD) exhibits a substantial comorbidity with anxiety and depression, with epidemiological studies highlighting their synergistic adverse effects on psychological well-being and quality of life of patients. We identified that the risk factors for anxiety and depression in patients with AD included educational level, frequency of medical visits, severity of pruritus, sleep disorders, allergic rhinitis, and asthma. Early recognition of these factors can enable targeted mental health prevention strategies and interventions that may benefit patients with AD by addressing modifiable risk factors.