Song ZY, Li N, Liu HB. Analysis of influencing factors on the nutritional status of non-dialysis elderly patients with chronic kidney disease and depression. World J Psychiatry 2025; 15(5): 102539 [DOI: 10.5498/wjp.v15.i5.102539]
Corresponding Author of This Article
Hong-Bao Liu, PhD, Doctor, Department of Nephrology, Tangdu Hospital, The Fourth Military Medical University (Air Force Medical University), No. 1 Xinsi Road, Baqiao District, Xi’an 710038, Shaanxi Province, China. xjsnlhb@fmmu.edu.cn
Research Domain of This Article
Urology & Nephrology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. May 19, 2025; 15(5): 102539 Published online May 19, 2025. doi: 10.5498/wjp.v15.i5.102539
Analysis of influencing factors on the nutritional status of non-dialysis elderly patients with chronic kidney disease and depression
Zi-Yu Song, Ni Li, Hong-Bao Liu
Zi-Yu Song, Ni Li, Hong-Bao Liu, Department of Nephrology, Tangdu Hospital, The Fourth Military Medical University (Air Force Medical University), Xi’an 710038, Shaanxi Province, China
Co-first authors: Zi-Yu Song and Ni Li.
Author contributions: Song ZY designed the research, wrote the first draft of the manuscript, conducted the analysis, and provided guidance for the research; Song ZY, Li N, and Liu HB contributed to conceiving the research and analyzing the data; All authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Tangdu Hospital, The Fourth Military Medical University (Air Force Medical University) (No. K202404-14).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Bao Liu, PhD, Doctor, Department of Nephrology, Tangdu Hospital, The Fourth Military Medical University (Air Force Medical University), No. 1 Xinsi Road, Baqiao District, Xi’an 710038, Shaanxi Province, China. xjsnlhb@fmmu.edu.cn
Received: January 10, 2025 Revised: March 7, 2025 Accepted: April 8, 2025 Published online: May 19, 2025 Processing time: 110 Days and 0.3 Hours
Core Tip
Core Tip: Malnutrition is prevalent among non-dialysis elderly patients with chronic kidney disease (CKD) and comorbid depression, which exacerbates disease progression, impairs prognosis, and undermines clinical outcomes. This study enrolled 182 non-dialysis elderly patients with CKD and depression to investigate nutritional status and analyze influencing factors. Results demonstrated that serum albumin (Alb), hemoglobin (Hb), and pre-albumin (PA) levels and anxiety symptoms independently influenced malnutrition risk in this cohort. Specifically, increased serum Alb, Hb, and PA levels were protective factors, whereas the presence of anxiety symptoms was a risk factor. Clinically, regular monitoring of serum Alb, Hb, and PA levels should be prioritized to guide timely nutritional interventions. Moreover, close observation and immediate psychological support should be provided for patients presenting with anxiety symptoms to effectively address their mental health needs.
