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Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Dec 19, 2021; 11(12): 1228-1238
Published online Dec 19, 2021. doi: 10.5498/wjp.v11.i12.1228
Newer antipsychotics: Brexpiprazole, cariprazine, and lumateperone: A pledge or another unkept promise?
Rajdip Barman, Pradipta Majumder, Tejaswini Doifode, Anita Kablinger
Rajdip Barman, Department of Psychiatry, Genesis Health System, Davenport, IA 52804, United States
Pradipta Majumder, Department of Psychiatry, WellSpan, York, PA 17420, United States
Tejaswini Doifode, Anita Kablinger, Department of Psychiatry and Behavioral Science, Carilion Clinic-Virginia Tech Carilion School of Medicine, Roanoke, VA 24014, United States
Author contributions: Majumder P, Barman R, and Doifode T performed the literature search with author Kablinger A as a consultant; Majumder P, Barman R, and Doifode T wrote the initial draft; Kablinger A provided feedback and elaboration on the manuscript; all authors approved the final version.
Conflict-of-interest statement: We do not have any conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rajdip Barman, MD, Attending Doctor, Department of Psychiatry, Genesis Health System, 1401 West Central Park Avenue, Davenport, IA 52804, United States. rajdip25in@gmail.com
Received: February 20, 2021
Peer-review started: February 20, 2021
First decision: July 15, 2021
Revised: July 28, 2021
Accepted: October 27, 2021
Article in press: October 27, 2021
Published online: December 19, 2021
Core Tip

Core Tip: In this review article we attempted to appraise the scientific literature on three newer antipsychotics such as brexpiprazole, cariprazine and lumateperone and presented their safety and efficacy data. Our aim was to investigate the status of these antipsychotic agents in treating various psychiatric disorders.