Published online Oct 19, 2021. doi: 10.5498/wjp.v11.i10.774
Peer-review started: February 27, 2021
First decision: July 15, 2021
Revised: July 16, 2021
Accepted: August 30, 2021
Article in press: August 30, 2021
Published online: October 19, 2021
Core Tip: Suicide is major public health concern worldwide, and at the same time, it is preventable when timely measures are taken. The biological basis of suicidal behaviour is not a product of a single gene, transcript, protein or metabolite; rather, it is represented by intertwined cellular mechanisms, cell types and tissue changes, and based on numerous molecular pathways. The ‘-omic’ technologies might represent the missing link between the current state of psychiatry and future personalised approaches, through the combination of -omics-derived information and the diagnostic process. However, first we need precise, specific and validated biomarkers.