Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2023; 13(11): 884-892
Published online Nov 19, 2023. doi: 10.5498/wjp.v13.i11.884
Independent risk factors for depression in older adult patients receiving peritoneal dialysis for chronic kidney disease
Yu-Ping Sheng, Xiao-Ying Ma, Ye Liu, Xing-Meng Yang, Fu-Yun Sun
Yu-Ping Sheng, Xiao-Ying Ma, Ye Liu, Xing-Meng Yang, Fu-Yun Sun, Department of Nephrology, Cangzhou Central Hospital, Cangzhou 061000, Hebei Province, China
Author contributions: Sheng YP, Ma XY, Liu Y, Yang XM and Sun FY designed the research; Sheng YP, Sun FY, Ma XY performed the research; Liu Y and Yang XM contributed new reagents/analytic tools; Sheng YP, Sun FY and Liu Y analyzed the data; Sheng YP, Sun FY and Ma XY wrote the paper.
Institutional review board statement: This study has passed the ethical review and approval of Cangzhou Central Hospital.
Informed consent statement: The study has obtained informed consent from the patient or the patient's guardian.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Fu-Yun Sun, MD, Attending Doctor, Department of Nephrology, Cangzhou Central Hospital, No. 16 Xinhua Road, Yunhe Distract, Cangzhou 061000, Hebei Province, China. 13315777305@163.com
Received: September 5, 2023
Peer-review started: September 5, 2023
First decision: September 14, 2023
Revised: September 22, 2023
Accepted: October 11, 2023
Article in press: October 11, 2023
Published online: November 19, 2023
ARTICLE HIGHLIGHTS
Research background

Previous studies demonstrated that over 20 million people in China experience decompensated kidney function, with 19.25% of them being older adults. Given the trend in global aging population, the proportion of older patients with chronic kidney disease (CKD) is expected to increase. Therefore, special attention should be focus on the treatment and prognosis of older patients with CKDs.

Research motivation

This study aimed to investigate the independent risk factors for depression in older patients with CKD undergoing peritoneal dialysis.

Research objectives

The study aimed to provide a clinical basis for the prevention of depression in older patients with CKDs.

Research methods

This retrospective study included a primary study population of 170 patients with CKD who received peritoneal dialysis from January 2020 to December 2022. We assessed the patients’ mental status using the Beck Depression Inventory Score-II, Self-Rating Anxiety Scale, Anxiety Inventory Score, and the Pittsburgh Sleep Quality Index. Logistic regression was employed to identify depression independent risk factors among these patients.

Research results

The results of this study suggest that years of education, sleep quality, anxiety status, comorbid diabetes, cardiovascular diseases, and anemia are independent risk factors for depression in older patients with CKDs.

Research conclusions

This study found that years of education, sleep quality, anxiety status, comorbid diabetes mellitus, cardiovascular disease, and anemia were independent risk factors for depression in older patients with CKDs, and future clinical management of patients should address these risk factors to prevent depression and improve prognosis.

Research perspectives

This study investigated the independent risk factors for depression in older patients with CKD to provide a scientific basis for improving their prognosis, as well as to reduce the risk of depression in old age.